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Mission Objective: Save + Revitalize Independent Pharmacy™

You Should Love Your Pharmacy System

Top 10 Reasons to Love PioneerRx Pharmacy Software



PioneerRx is backed by a family-owned company that has been passionate about independent pharmacy since 1841.


MTM/5-Star Ratings

Improve your patients’ health and increase profit/revenue with our integrated features, including Mirixa, OutcomesMTM, built-in labs, and immunization.


Integrated Point of Sale

With a truly integrated point of sale, you have direct access to pricing and patient information, seamlessly becoming part of your workflow.


Quick Disaster Recovery

Your pharmacy’s data is backed up to the Cloud –that means meeting HIPAA requirements and minimizing downtime in the event of an emergency.


Rapid Data Entry

With PioneerRx, you can customize your tab stops, use keyboard shortcuts, pull information from the NPI/DEA database, and easily fill prescriptions from eScripts. These are all key features that save you time.


Everyone is Doing It

Did you know, 50% of our sales are referrals from existing customers whose pharmacies have been empowered by PioneerRx?


Rapid Innovation

From weekly automatic software and database updates, to our user-driven Community Idea portal, we deliver cutting-edge technology in one integrated solution.


Healthier Patients

With our integrated Rx Syncing and easy search features, you can efficiently improve your patients’ health and adherence, which also enables you to better participate in your patients’ wellness.


Maximize Profits

PioneerRx’s customers will tell you they are making more money and having more fun!

Number 1 Reason to Love PioneerRx


User-Driven Features

In the last year, we averaged 13 new updates every week. Most of those updates are inspired by you! Our pharmacy owners, pharmacists, pharmacy techs and pharmacy staff play a huge role in our weekly innovation.

According to a 2018 Independent Survey

These Facts Speak for Themselves

Ranked #1 in Customer Satisfaction


Their satisfaction is a direct reflection on how PioneerRx is servicing our industry. Are you satisfied with your current pharmacy software?

Most Installed Pharmacy Software


It’s no secret that PioneerRx is the most advanced, innovative and intuitive pharmacy software on the market. Isn’t it time to see it in action?


December Installations


New Locations

Installed PioneerRx



Join the Wave

Watch "Can you predict your future?"

Can you predict your future?

PioneerRx helps Independent Pharmacies create their own future.

President of PioneerRx Pharmacy Software, Jeff Key inspires PDS members to out-innovate their Goliath. Today’s answers will not work on tomorrows test. Investing in the right people and the right tools will help independent pharmacy have a future.



Join the Movement

PioneerRx is about more than pharmacy software, we have taken on the personal pursuit to Save + Revitalize our industry. But, it’s going to take a community of pharmacy leaders, regardless of the software they use. We’d like to introduce them to you. Click below and learn more about how these creative pharmacy leaders are doing their part to Save + Revitalize Independent Pharmacy.

Mike Matovich

Featured Movement Leader

“I found out how enjoyable pharmacy was when you don’t have the constraints of the chain telling you what to do. You really get to start thinking outside the box and you can really shape the direction you want to take your business.”

From the Blog

Featured Articles

Ensure Therapeutic Equivalency with PioneerRx

Ensure Therapeutic Equivalency with PioneerRx

Generic substitution is a common and necessary practice in pharmacies across the United States. According to the 2018 Generic Drug Access and Savings Report, 9 out of 10 dispensed drugs were generics, which saved patients a collective $265 billion in 2017. Generic drugs are usually more affordable and accessible than their brand name equivalents, making… Read more

The four essientials for pioneerrx users blog graphic

4 Essentials for New PioneerRx Users

With a new year approaching, you may be considering some changes around your pharmacy. Whether you’re seeking a new pharmacy software system or some different services for your patients, there’s no better time than now to implement these changes. Like any new technology purchase or practice you want to put into action… Read more

Putting Sickness to the Test

Access to excellent healthcare is an ongoing need in the United States, especially during colder seasons when sickness increases. If future seasonal illnesses are as prevalent as they were in 2017, doctor’s offices and emergency rooms will flood with patients seeking relief from influenza and strep throat. The state of Kentucky sought to solve this… Read more

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