PioneerRx Pharmacy Software has partnered with Tabula Rasa HealthCare (TRHC) to offer TRHC’s MedWise™ medication safety software to PioneerRx pharmacies.

This partnership will not only allow pharmacies to improve their patients’ health outcomes by preventing adverse drug events (ADEs), butit also will lead to a strong retention of patients through the establishment of personalized medication regimens.

Having access to this medication decision support tool will enable pharmacists to educate patients on the importance of the safe use of medication and create a demand for personalized medication management.

“Because pharmacists are the only professionals who learn about and practice medication disposition sciences in school,” explains TRHC Chairman and CEO Calvin H. Knowlton, PhD. “Pharmacists have a unique understanding of the pharmacokinetics, pharmacogenomics and pharmacodynamics behind drug interactions, and MedWise empowers them to use this knowledge to get actionable clinical insights. By integrating MedWise with PioneerRx, pharmacies will have access to this robust software directly within their patient profiles to make informed medication decisions.”

Instead of using an outdated one-to-one drug interaction system, MedWise uses a science-backed approach to simultaneously analyze multi-drug interactions resulting in a MedWise Risk Score™ (MRS).

“We built this digital hub that…can tell the pharmacist before they dispense a medication whether it is going to be a problem, or not, based on the other drugs in a patient’s profile, or even due to a patient’s genetic makeup,” says Knowlton.

The MRS aims to reduce trial-and-error prescribing, and instead, looks at an individual’s unique medication profile to get a clear understanding of how the body will react to the drugs prescribed.

“We want pharmacists to use what they learned in school to leapfrog evidence-based medication prescribing, which is not customized for each patient, and to instead provide personalized medication,” Knowlton advocates.

A published study involving more than almost 2,000 Part D individuals found that a lower MRS correlated with fewer ADEs, emergency visits, hospitalizations, and over $1,000 in annual medical cost reduction per unit of the MRS.

Offering enhanced medication management sessions with MedWise and the MRS presents an opportunity for pharmacies to add an additional revenue stream.

TRHC has a support team of board-certified pharmacists available to help analyze a patient’s MedWise results and offer any guidance to pharmacies.  Ultimately, pharmacists can choose to take TRHC’s certification course – which offers CE credits – and receive MedWise Advisor certification.

This demonstrates a benefit that a pharmacist can offer patients.

MedWise also is available in a mobile app, whereby patients can input new over-the-counter and other medications into their profile to see if any potential interactions could occur before taking them.

“This is a way patients can be tethered to their local pharmacy,” emphasizes Knowlton. “MedWise presents pharmacists with an option to provide a concierge-type service, which is an upscale practice of pharmacy available to consumers and caregivers.”

By instituting MedWise and becoming a dependable source of personalized pharmacotherapy, pharmacists can better retain their patients and create a sustainable future for their pharmacy.

PioneerRx’s partnership with Tabula Rasa HealthCare will facilitate access to the MedWise software and offer a powerful addition to participating pharmacies.\

About PioneerRx:

PioneerRx is committed to saving and revitalizing independent pharmacy. With unmatched customer support and continuous updates, PioneerRx Pharmacy Software equips pharmacies to thrive in a clinical, patient-centered future. By implementing suggestions from users and paving the way for leading industry trends, they empower  pharmacies for continued success and improved patient outcomes. To see why PioneerRx is the most installed independent pharmacy software, visit

About Tabula Rasa HealthCare:

TRHC is a leader in providing patient-specific, data-driven technology and solutions that enable healthcare organizations to optimize medication regimens to improve patient outcomes, reduce hospitalizations, lower healthcare costs and manage risk. TRHC provides solutions for a range of payers, providers and other healthcare organizations. For more information, visit

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Arnela Jusupovic


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